When a Single Average Effect Is the Wrong Summary of an Intervention

Every intervention study carries an implicit promise: that the number it reports will tell us something true about the people it studied. Yet when researchers collapse dozens of heterogeneous participants into one grand average, that promise quietly breaks. A pooled...

Can Conformal Prediction Make Large-Scale Hypothesis Testing Safer?

Modern science has become an exercise in mass interrogation. A single genomics experiment can probe twenty thousand genes at once, a clinical trial may monitor hundreds of biomarkers simultaneously, and a neuroimaging study can test tens of thousands of voxels in a...